Patients may be diagnosed with persistent Müllerian duct syndrome. If a male fetus doesn’t make enough AMH, the Müllerian duct doesn’t disappear, which can lead to abnormal development of the reproductive system.
AMH levels can be measured to determine how many follicles a woman has in her ovaries. A high number of ovarian follicles means the ovaries can produce larger amounts of AMH.
Follicles hold and support eggs before fertilization. Within the ovaries, it helps in the early development of follicles. If a fetus has XX (female) chromosomes, a lack of testosterone will cause the Wollfian duct to vanish and the Müllerian duct will develop into the female reproductive system.ĪMH also has role in puberty and in adult ovaries and testes. Then, testosterone produced in the testes will promote the development of the male reproductive system. If the fetus has XY (male) chromosomes, the testes will produce AMH and the Müllerian ducts will disappear. Around eight weeks after conception, a fetus has both Müllerian (female) and Wollfian (male) ducts, which can develop into the male or female reproductive system. Prior to birth, AMH is made in the fetus’ testes and ovaries. This hormone assists in a male fetus’ reproductive development. During pregancy, the anti-Müllerian hormone (AMH) is essential in fetal development. Women are born with their lifetime supply of eggs but these decrease with age. Anti-Müllerian Hormone (AMH) acts as the gatekeeper for fertility and reproductive development.
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